Santa Fe Style Interior Design: 4 Hotel Interiors That Define Southwestern Living

Bright blue wooden fence with autumn yellow desert blooms in Santa Fe, New Mexico

Santa Fe is unlike anywhere else in the United States. It’s a place where art, architecture, and desert landscapes come together in the most soulful way. From adobe textures and handwoven rugs to wrought iron lighting and bold folk art, the design style here is layered, earthy, and endlessly inspiring.

On a recent trip, I stayed at the Inn and Spa at Loretto, right next to the historic Loretto Chapel, home to the famed spiral staircase built without nails or visible support. Walking through the chapel, with its warm light and impossibly engineered staircase, felt like stepping into a living design story. That blend of mystery, craftsmanship, and Southwest character is exactly what these hotels capture.

Here are four standout Santa Fe hotels where the interiors reflect the soul of the city and how to bring those design ideas home.


Rosewood Inn of the Anasazi – Desert Elegance

Rosewood Inn of the Anasazi

Neighborhood: Downtown Santa Fe
Design Vibe: Refined rustic with Native American influences

This upscale stay blends leather, warm wood, and woven textures for a grounded yet elevated look.

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Capture Rosewood’s Style

  • Decor that blends heritage with comfort

  • Leather seating, natural materials, and neutral warmth

  • Layered textiles and handcrafted details

Want to experience the Rosewood Inn of the Anasazi Hotel for yourself? Check rates on Expedia


El Rey Court – Retro Desert Cool

El Rey Court

Neighborhood: Cerrillos Road
Design Vibe: Midcentury Southwest meets motel chic

A retro roadside inn with colorful accents, vintage furniture, and desert-cool energy.

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Capture El Rey’s Style

  • Mix retro furniture with earth tones

  • Use pops of color to modernize rustic textures

  • Add playful touches with art and textiles

Want to experience El Rey Court for yourself? Check rates on Expedia


Hotel St. Francis – Mission Minimalism

Hotel St. Francis

Neighborhood: Historic District
Design Vibe: Spiritual simplicity with monastic undertones

Minimalist rooms with carved furniture, aged neutrals, and religious iconography.

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Capture Hotel St. Francis’ Style

  • Aged neutrals, whitewashed wood, and hand-forged metals

  • Keep things spare but meaningful

  • Include spiritual or cultural symbols for impact

Want to experience The Hotel St. Francis for yourself? Check rates on Expedia


Inn and Spa at Loretto – Sacred Craft

Inn and Spa at Loretto

Neighborhood: Near Loretto Chapel / Historic Plaza
Design Vibe: Pueblo Revival elegance meets artistic heritage

Pueblo-style architecture with adobe walls, rustic beams, and spiritual artistry throughout.

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Capture the Inn & Spa at Loretto’s Style

  • Embrace architectural drama with warmth and history

  • Use hand-carved wood and iron accents

  • Let heritage inform focal design pieces

Want to experience the Inn & Spa at Loretto for yourself? Check rates on Expedia


Bringing Santa Fe Style Home

Southwestern interior design isn’t about following trends, it’s about grounding your space in natural textures, personal history, and a sense of place. These Santa Fe hotels show how warmth, tradition, and artistry can coexist beautifully. Whether you're drawn to handcrafted woodwork, desert hues, or mission-style simplicity, let these interiors inspire your next design move.

Want more design inspiration? Check out my full Santa Fe Hotel Guide for stylish places to stay across the city.

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